HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → Ethyl 2-bromo-4-fluoro-5-nitrobenzyl ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-Bromo-1-(ethoxymethyl)-4-fluorobenzene | HCID 20032356 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | Ethyl 2-bromo-4-fluoro-5-nitrobenzyl ether | HCID 20032353 | — |
Reaction Steps
By the method of Example 2, Step D, 7.18 g (0.0308 mole) of ethyl 2-bromo-4-fluoro benzyl ether, 2 ml of fuming nitric acid, and 18 ml of concentrated sulfuric acid were reacted in 20 ml of 1,2-dichloroethane, yielding 3.1 g of ethyl 2-bromo-4-fluoro-5-nitrobenzyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04846882 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-0e3831de4bf74c01a4a48d3bd575b357 |
| Source note | uspto-grants-1989_07 |