Thionyl Chloride → HCID 20032671, compound

HRID 231456Notes

Reaction equation

HRID 231456 reaction equation
[CH3:1][CH:2]1[CH2:7][CH:6]([CH2:8][CH2:9][CH3:10])[CH2:5][CH2:4][CH:3]1[C:11]1[CH:19]=[CH:18][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=1.O=S(Cl)Cl>>[CH3:1][CH:2]1[CH2:7][CH:6]([CH2:8][CH2:9][CH3:10])[CH2:5][CH2:4][CH:3]1[C:11]1[CH:19]=[CH:18][C:14]([C:15]([O:17][C:6]2[CH:5]=[CH:4][C:3]([CH2:11][CH3:12])=[CH:2][CH:7]=2)=[O:16])=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 20032577HCID 20032577, compound

Product 1

HCID 20032671HCID 20032671, compound

Procedure

20 g of p-(2-methyl-4-n-propylcyclohexyl)-benzoic acid (Examaple 5) is boiled for 1 hour with 24 g of SOCl2, the mixture is evaporated to dryness, the resulting crude acid chloride is dissolved in 150 ml of toluene, to which are added 8 ml of pyridine and 13.2 g of ethylphenol, and the mixture is boiled for 2 hours. Cooling down and customary working up give p-ethylphenyl p-(2-methyl-4-n-propylcyclohexyl)-benzoate.

Workup

  1. customthe mixture is evaporated to dryness
  2. dissolutionthe resulting crude acid chloride is dissolved in 150 ml of toluene, to which
  3. additionare added 8 ml of pyridine and 13.2 g of ethylphenol
  4. temperatureCooling down and

Sources & evidence

ORD record
ord-7617bf0ad417493a8f35aaf376a8d6fd
Source dataset
uspto-grants-1989_07
Patent number
US04846998

Reaction notes

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