Ethanol → 4-{2-[5-(2-Aminomethyl-4-fluorophenoxy)-indazol-1-yl]-ethyl}-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[BH4-:47].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][n:16]2[n:17][cH:18][c:19]3[cH:20][c:21]([O:25][c:26]4[c:27]([C:33]#[N:34])[cH:28][c:29]([F:32])[cH:30][cH:31]4)[cH:22][cH:23][c:24]23)[CH2:12][CH2:13]1.[CH3:49][CH2:50][OH:51].[Na+:48].[n:35]1[cH:36][cH:37][cH:38][cH:39][c:40]1-[c:41]1[cH:42][cH:43][cH:44][cH:45][n:46]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][n:16]2[n:17][cH:18][c:19]3[cH:20][c:21]([O:25][c:26]4[c:27]([CH2:33][NH2:34])[cH:28][c:29]([F:32])[cH:30][cH:31]4)[cH:22][cH:23][c:24]23)[CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9625c360b6b4469a8f44965cf7a2403a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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