Dimethylformamide → 3-bromo-N-[6-(3,3-dimethylbutylamino)-3-hydroxy-5-methyl-6-oxo-1-phenylhexan-2-yl]-4-fluorobenzamide
Reaction equation
[Br:11][c:12]1[cH:13][c:14]([C:15](=[O:16])[OH:17])[cH:18][cH:19][c:20]1[F:21].[CH3:22][C:23]([CH2:24][CH2:25][NH:26][C:27]([CH:28]([CH2:29][CH:30]([CH:31]([CH2:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[NH2:39])[OH:40])[CH3:41])=[O:42])([CH3:43])[CH3:44].[Cl:50][CH2:51][Cl:52].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49].[OH:1][n:2]1[c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[n:9][n:10]1>>[Br:11][c:12]1[cH:13][c:14]([C:15](=[O:17])[NH:39][CH:31]([CH:30]([CH2:29][CH:28]([C:27]([NH:26][CH2:25][CH2:24][C:23]([CH3:22])([CH3:43])[CH3:44])=[O:42])[CH3:41])[OH:40])[CH2:32][c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:18][cH:19][c:20]1[F:21]Participants
6
Sources & evidence
- ORD record
- ord-ae889bee0a094e7d9432a6ea192d914c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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