Dichloromethane → 3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]prop-2-enenitrile
Reaction equation
[CH:1]1([C:6](=[CH:7][C:8]#[N:9])[n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[n:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:22][cH:23]4)[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:32][CH2:33][Cl:34].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[CH:1]1([C:6](=[CH:7][C:8]#[N:9])[n:10]2[n:11][cH:12][c:13](-[c:15]3[c:16]4[c:17]([n:18][cH:19][n:20]3)[nH:21][cH:22][cH:23]4)[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
4
Sources & evidence
- ORD record
- ord-bb7c856a706f43899e86b2ed04b26019
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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