Dimethylformamide dimethyl acetal → HCID 1482231, compound

HRID 231524Notes

Reaction equation

HRID 231524 reaction equation
[C:1]([CH2:7][C:8]#[N:9])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].CO[CH:12](OC)[N:13]([CH3:15])[CH3:14]>>[CH3:15][N:13]([CH:12]=[C:7]([C:1](=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3])[C:8]#[N:9])[CH3:14]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 108871Pentanenitrile, 4,4-dimethyl-3-oxo-

Product 1

HCID 1482231HCID 1482231, compound

Procedure

A mixture of 25.0 g of pivaloyl acetonitrile in 50 ml of N,N-dimethylformamide dimethyl acetal was stirred at room temperature for 8 hours under argon and then the solvent was evaporated and n-hexane was added with stirring. The product was collected by filtration to give 34.6 g of 2-[(dimethylamino)methylene]-4,4-dimethyl-3-oxopentanenitrile.

Workup

  1. customthe solvent was evaporated
  2. additionn-hexane was added
  3. stirringwith stirring
  4. filtrationThe product was collected by filtration

Sources & evidence

ORD record
ord-28ffbcc007954a95b8d8cc07a1e25778
Source dataset
uspto-grants-1989_07
Patent number
US04847256

Reaction notes

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