Dimethylformamide → 3-Chloro-3-(4-chlorophenyl)-2-propylisoindolin-1-one

HRID 2315254Notes

Reaction equation

HRID 2315254 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([OH:21])[N:9]([CH2:18][CH2:19][CH3:20])[C:10](=[O:17])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:6][cH:7]1.[O:26]=[CH:27][N:28]([CH3:29])[CH3:30].[S:22]([Cl:23])([Cl:24])=[O:25]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([Cl:24])[N:9]([CH2:18][CH2:19][CH3:20])[C:10](=[O:17])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 513495613-(4-Chlorophenyl)-3-hydroxy-2-propylisoindolin-1-one

Product 1

HCID 513512563-Chloro-3-(4-chlorophenyl)-2-propylisoindolin-1-one

Sources & evidence

ORD record
ord-df8f22e632934049b622e4a08d8dda09
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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