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HRID23154

反应详情

EQUATION

反应方程式

HRID 23154 的结构方程式

REACTANTS

反应物

2
结构：CN(C)CCN
HCID66053

N,N-Dimethylethylenediamine

C4H12N2

结构：COC(=O)c1cc2ccc([N+](=O)[O-])cc2[nH]1
HCID11816863

Methyl 6-nitro-1H-indole-2-carboxylate

C10H8N2O4

PRODUCTS

生成物

1
结构：CN(C)CCNC(=O)c1cc2ccc([N+](=O)[O-])cc2[nH]1
HCID85801420

未命名化合物

收率 84%

PROCEDURE

实验过程

500 mg (2.27 mmole) 6-Nitro-1H-indole-2-carboxylic acid methyl ester was dissolved in 4 mL neat N1,N1-dimethyl-ethane-1,2-diamine, was kept at 55° C. overnight and was evaporated. The oily residue was triturated with n-hexane to give 528 mg (84%) yellow solid which was no further purified. MS: 277.13 (calcd for M+H+:277.13)

WORKUP

后处理

  1. customwas evaporated
  2. customThe oily residue was triturated with n-hexane