Methanol → N2-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-4-(4-fluorophenyl)-N6-methyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

HRID 2315401Notes

Reaction equation

HRID 2315401 reaction equation
[C:1](#[N:2])[BH3-:3].[CH3:39][OH:40].[CH3:5][NH2:6].[Cl:7][c:8]1[n:9][cH:10][n:11](-[c:13]2[c:14]([O:37][CH3:38])[cH:15][c:16]([NH:19][c:20]3[s:21][c:22]4[c:23]([n:24]3)[CH:25]([c:30]3[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]3)[CH2:26][C:27](=[O:29])[CH2:28]4)[cH:17][cH:18]2)[cH:12]1.[Na+:4]>>[CH3:1][NH:2][CH:27]1[CH2:26][CH:25]([c:30]2[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]2)[c:23]2[c:22]([s:21][c:20]([NH:19][c:16]3[cH:15][c:14]([O:37][CH3:38])[c:13](-[n:11]4[cH:10][n:9][c:8]([Cl:7])[cH:12]4)[cH:18][cH:17]3)[n:24]2)[CH2:28]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 6329MethylamineHCID 498716Cyano-borohydrideHCID 581100012-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenylamino)-4-(4-fluorophenyl)-4,5-dihydrobenzo[d]thiazol-6(7H)-one

Product 1

HCID 46864518N2-(4-(4-chloro-1H-imidazol-1-yl)-3-methoxyphenyl)-4-(4-fluorophenyl)-N6-methyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

Sources & evidence

ORD record
ord-47723ddaa25a412daa56f66112938263
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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