Diisopropylethylamine → ethyl 4-(aminomethyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylate

HRID 2315711Notes

Reaction equation

HRID 2315711 reaction equation
[CH2:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH:6]([CH3:7])[CH3:8])[CH3:9].[Cl:23][c:24]1[c:25]2[c:26]([n:27][cH:28][n:29]1)[nH:30][cH:31][cH:32]2.[NH2:10][CH2:11][C:12]1([C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1>>[NH2:10][CH2:11][C:12]1([C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH2:13][CH2:14][N:15]([c:24]2[c:25]3[c:26]([n:27][cH:28][n:29]2)[nH:30][cH:31][cH:32]3)[CH2:16][CH2:17]1

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-HCID 57750280Ethyl 4-(aminomethyl)piperidine-4-carboxylate

Product 1

HCID 57750365ethyl 4-(aminomethyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylate

Sources & evidence

ORD record
ord-aa2c5c1cfc20484380803f1d6c83080a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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