Ethyl Acetate → Tert-butyl {1-[4-(5-hydrazino-3-phenyl-1,6-naphthyridin-2-yl)phenyl]cyclobutyl}carbamate

HRID 2315969Notes

Reaction equation

HRID 2315969 reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][O:48][CH2:49]1.[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:3][c:4]1[c:5]2[cH:6][c:7](-[c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[c:8](-[c:14]3[cH:15][cH:16][c:17]([C:20]4([NH:24][C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:21][CH2:22][CH2:23]4)[cH:18][cH:19]3)[n:9][c:10]2[cH:11][cH:12][n:13]1.[NH2:1][NH2:2]>>[NH:1]([NH2:2])[c:4]1[c:5]2[cH:6][c:7](-[c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[c:8](-[c:14]3[cH:15][cH:16][c:17]([C:20]4([NH:24][C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:21][CH2:22][CH2:23]4)[cH:18][cH:19]3)[n:9][c:10]2[cH:11][cH:12][n:13]1

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 9321HydrazineHCID 312751,4-DioxaneHCID 57805456HCID 57805456, compound

Product 1

HCID 57805468Tert-butyl {1-[4-(5-hydrazino-3-phenyl-1,6-naphthyridin-2-yl)phenyl]cyclobutyl}carbamate

Sources & evidence

ORD record
ord-e573fc34e0c34f1bb509b14fa1fdb461
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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