Isopropanol → 2-[5-Chloro-2-(7,7-difluoro-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-ylamino)-pyrimidin-4-ylamino]-N-methyl-benzamide
Reaction equation
[CH:34]([OH:35])([CH3:36])[CH3:37].[Cl:15][c:16]1[n:17][cH:18][c:19]([Cl:33])[c:20]([NH:22][c:23]2[c:24]([C:25](=[O:26])[NH:27][CH3:28])[cH:29][cH:30][cH:31][cH:32]2)[n:21]1.[F:1][C:2]1([F:14])[CH2:3][CH2:4][c:5]2[c:6]([cH:9][c:10]([NH2:13])[cH:11][cH:12]2)[CH2:7][CH2:8]1>>[F:1][C:2]1([F:14])[CH2:3][CH2:4][c:5]2[c:6]([cH:9][c:10]([NH:13][c:16]3[n:17][cH:18][c:19]([Cl:33])[c:20]([NH:22][c:23]4[c:24]([C:25](=[O:26])[NH:27][CH3:28])[cH:29][cH:30][cH:31][cH:32]4)[n:21]3)[cH:11][cH:12]2)[CH2:7][CH2:8]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-1b9c1fc045744efdb1f51c243c02bc8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…