Water → 5-Amino-2-(2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-2H-isoquinolin-1-one

HRID 2316256Notes

Reaction equation

HRID 2316256 reaction equation
[O:1]1[CH2:2][CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][c:9]([CH2:11][n:12]1[c:13](=[O:25])[c:14]3[cH:15][cH:16][cH:17][c:18]([N+:22]([O-:23])=[O:24])[c:19]3[cH:20][cH:21]1)[cH:10]2.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:26].[OH2:27].[Sn:28]([Cl:29])[Cl:30]>>[O:1]1[CH2:2][CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][c:9]([CH2:11][n:12]1[c:13](=[O:25])[c:14]3[cH:15][cH:16][cH:17][c:18]([NH2:22])[c:19]3[cH:20][cH:21]1)[cH:10]2

Participants

5

Reactant 4

HCID 962Water2×HCID 8028TetrahydrofuranHCID 24479Stannous ChlorideHCID 582704062-(2,3-Dihydro-benzo[1,4]dioxin-6-ylmethyl)-5-nitro-2H-isoquinolin-1-one

Product 1

HCID 582704495-Amino-2-(2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-2H-isoquinolin-1-one

Sources & evidence

ORD record
ord-13bc790bb930491c92d7ee99bb079a62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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