Tetrahydrofuran → 4-Hydroxy-4-(3-(1-hydroxyethyl)benzo[b]thiophen-2-yl)-1-(t-butyloxycarbonyl)piperidine
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]1.[CH2:13]([Li:14])[CH2:15][CH2:16][CH3:17].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[OH:1][CH:2]([CH3:3])[c:4]1[c:5]2[c:6]([s:7][cH:8]1)[cH:9][cH:10][cH:11][cH:12]2>>[OH:1][CH:2]([CH3:3])[c:4]1[c:5]2[c:6]([s:7][c:8]1[C:28]1([OH:31])[CH2:27][CH2:26][N:25]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[CH2:30][CH2:29]1)[cH:9][cH:10][cH:11][cH:12]2Participants
5
Sources & evidence
- ORD record
- ord-d6aeea6a173e4661bd1851c4b7ffec7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…