Tetrahydrofuran → 4-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

HRID 2316395Notes

Reaction equation

HRID 2316395 reaction equation
[C:1](#[N:2])[c:3]1[c:4]([C:20]([F:21])([F:22])[F:23])[cH:5][c:6]([N:9]([CH2:10][C:11](=[O:12])[O:13][CH3:14])[CH2:15][C:16]([F:17])([F:18])[F:19])[cH:7][cH:8]1.[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1>>[C:1](#[N:2])[c:3]1[c:4]([C:20]([F:21])([F:22])[F:23])[cH:5][c:6]([N:9]([CH2:10][CH2:11][OH:12])[CH2:15][C:16]([F:17])([F:18])[F:19])[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 11439223Methyl N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)glycinate

Product 1

HCID 866237314-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

Sources & evidence

ORD record
ord-4b6e377a64db4faf9f8458462cd5ab66
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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