Dichloromethane → 4-{2-[4-Butyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethoxy}-2-chloro-benzonitrile
Reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][c:7](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[s:8][c:9]1[CH2:10][CH2:11][OH:12].[Cl:23][c:24]1[c:25]([C:26]#[N:27])[cH:28][cH:29][c:30]([OH:32])[cH:31]1.[Cl:52][CH2:53][Cl:54].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[c:5]1[n:6][c:7](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[s:8][c:9]1[CH2:10][CH2:11][O:12][c:30]1[cH:29][cH:28][c:25]([C:26]#[N:27])[c:24]([Cl:23])[cH:31]1Participants
5
Sources & evidence
- ORD record
- ord-0c386d8f14de4c4883f40f9f28eb9f53
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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