Water → Ethyl 3-cyano-3-(3,4-dichlorophenyl)-5-(tetrahydropyran-2-yloxy)pentanoate
Reaction equation
[CH2:33]([CH3:34])[O:35][C:36]([CH2:37][Br:38])=[O:39].[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl:13][c:14]1[cH:15][c:16]([CH:21]([C:22]#[N:23])[CH2:24][CH2:25][O:26][CH:27]2[O:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[cH:17][cH:18][c:19]1[Cl:20].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1.[OH2:45]>>[Cl:13][c:14]1[cH:15][c:16]([C:21]([C:22]#[N:23])([CH2:24][CH2:25][O:26][CH:27]2[O:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[CH2:37][C:36]([O:35][CH2:33][CH3:34])=[O:39])[cH:17][cH:18][c:19]1[Cl:20]Participants
7
Sources & evidence
- ORD record
- ord-4a0756c9eaeb4e6ea32625f754c730f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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