Ammonia → 3-[4-[2-(difluoromethyl)-4-methoxy-1H-benzimidazol-1-yl]-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-8-oxa-3-azabicyclo[3.2.1]octane
Reaction equation
[Cl:50][CH2:51][Cl:52].[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:22]3[CH2:23][CH2:24][N:25]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH2:26][CH2:27]3)[n:11][c:12]([N:14]3[CH2:15][CH:16]4[CH2:17][CH2:18][CH:19]([CH2:20]3)[O:21]4)[n:13]1)[cH:35][cH:36][cH:37][c:38]2[O:39][CH3:40])[F:41].[F:42][C:43]([F:44])([F:45])[C:46]([OH:47])=[O:48].[NH3:49]>>[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:22]3[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]3)[n:11][c:12]([N:14]3[CH2:15][CH:16]4[CH2:17][CH2:18][CH:19]([CH2:20]3)[O:21]4)[n:13]1)[cH:35][cH:36][cH:37][c:38]2[O:39][CH3:40])[F:41]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1bfbbc97d8c24369a51cca4e2aa1341c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…