Hydrochloric Acid → 1-(Tert-butoxycarbonyl)-4-(4-chloro-3-fluorophenyl)piperidine-4-carboxylic acid
Reaction equation
[Cl:1][c:2]1[c:3]([F:23])[cH:4][c:5]([C:8]2([C:21]#[N:22])[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[ClH:24].[Na+:26].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1.[OH-:25].[OH2:33]>>[Cl:1][c:2]1[c:3]([F:23])[cH:4][c:5]([C:8]2([C:21](=[O:25])[OH:33])[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-58195cbe6af643f28c23b10f0f58a981
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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