Sulfuric Acid → HCID 88521943, compound

Participants

Reaction Steps

Acetic anhydride (7.34 g, 0.072 mol) was added to (4-cyano-2-fluorophenylthio)thiophene (8.46 g, 0.036 mol) in 200 ml ethyl acetate at 0° C. A cooled solution of sulfuric acid (3.88 g, 0.0395 mol) and ethyl acetate (10 ml) was added dropwise and allowed to stir at room temperature overnight. After cooling to 0° C. potassium acetate (4.23 g, 0.043 mol) in a minimum amount of ethanol was added slowly. A white solid (11.70 g) was collected after stirring one hour.

Provenance & Evidence