Dichloromethane → 2-[3-(4-Trifluoromethyl-phenyl)-1-(3-isopropoxy-benzoyl)-pyrrolidin-3-yl]-ethyl-bromide
Reaction equation
[C:31]([Br:32])([Br:33])([Br:34])[Br:35].[Cl:55][CH2:56][Cl:57].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]2([CH2:26][CH2:27][OH:28])[CH2:10][N:11]([C:14]([c:15]3[cH:16][c:17]([O:21][CH:22]([CH3:23])[CH3:24])[cH:18][cH:19][cH:20]3)=[O:25])[CH2:12][CH2:13]2)[cH:7][cH:8]1)([F:29])[F:30].[c:36]1([P:37]([c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[cH:50][cH:51][cH:52][cH:53][cH:54]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]2([CH2:26][CH2:27][Br:32])[CH2:10][N:11]([C:14]([c:15]3[cH:16][c:17]([O:21][CH:22]([CH3:23])[CH3:24])[cH:18][cH:19][cH:20]3)=[O:25])[CH2:12][CH2:13]2)[cH:7][cH:8]1)([F:29])[F:30]Participants
5
Sources & evidence
- ORD record
- ord-ee0fdfb47e394b4189539f5871e9380f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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