Phosphorus oxychloride → 5-chloro-2-(trifluoromethyl)-1,8-Naphthyridine
Reaction equation
[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([OH:13])[cH:8][cH:9][n:10][c:11]2[n:12]1)([F:14])[F:15].[P:16]([Cl:17])([Cl:18])([Cl:19])=[O:20]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([Cl:18])[cH:8][cH:9][n:10][c:11]2[n:12]1)([F:14])[F:15]Participants
3
Sources & evidence
- ORD record
- ord-791263e591974508be4fd14ff92ddded
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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