Dichloromethane → 1-{4-[4-(Azepane-1-carbonyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethanone

HRID 2317270Notes

Reaction equation

HRID 2317270 reaction equation
[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[CH3:28][C:29]([Cl:30])=[O:31].[Cl:32][CH2:33][Cl:34].[N:1]1([C:8](=[O:9])[c:10]2[cH:11][s:12][c:13]([C:15]3=[CH:20][CH2:19][NH:18][CH2:17][CH2:16]3)[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1>>[N:1]1([C:8](=[O:9])[c:10]2[cH:11][s:12][c:13]([C:15]3=[CH:20][CH2:19][N:18]([C:29]([CH3:28])=[O:31])[CH2:17][CH2:16]3)[cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 59542518Azepan-1-yl-[5-(1,2,3,6-tetrahydro-pyridin-4-yl)-thiophen-3-yl]-methanone

Product 1

HCID 426448311-{4-[4-(Azepane-1-carbonyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethanone

Sources & evidence

ORD record
ord-0bb6dc3588ad446b9e3d59b107456654
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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