Dichloromethane → N-[[1-(Dimethylamino)cyclopentyl](phenyl)methyl]-2-methyl-4,6-bis(trifluoromethyl)benzamide

HRID 2317403Notes

Reaction equation

HRID 2317403 reaction equation
[CH3:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[c:7]([C:15]([F:16])([F:17])[F:18])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1.[CH3:53][O:54][c:55]1[cH:56][c:57]([C:58]([F:59])([F:60])[F:61])[cH:62][c:63]([C:64]([F:65])([F:66])[F:67])[c:68]1[C:69]([NH:70][CH:71]([c:72]1[cH:73][cH:74][cH:75][cH:76][cH:77]1)[C:78]([CH3:79])([N:80]1[CH2:81][CH2:82][CH2:83][CH2:84]1)[CH2:85][CH3:86])=[O:87].[CH3:88][CH2:89][N:90]([CH2:91][CH3:92])[CH2:93][CH3:94].[Cl:95][CH2:96][Cl:97].[F:19][C:20]([F:21])([F:22])[c:23]1[cH:24][c:25]([C:26]([F:27])([F:28])[F:29])[cH:30][cH:31][c:32]1[C:33]([O:34][CH3:35])=[O:36].[NH2:37][CH:38]([C:39]1([N:44]([CH3:45])[CH3:46])[CH2:40][CH2:41][CH2:42][CH2:43]1)[c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1>>[CH3:1][c:2]1[c:3]([C:4](=[O:5])[NH:37][CH:38]([C:39]2([N:44]([CH3:45])[CH3:46])[CH2:40][CH2:41][CH2:42][CH2:43]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:7]([C:15]([F:16])([F:17])[F:18])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 11521393{1-[Amino(phenyl)methyl]cyclopentyl}dimethylamineHCID 18925643Methyl 2,4-bis(trifluoromethyl)benzoateHCID 59347787HCID 59347787, compoundHCID 59347796(+/-)-2-(Methyloxy)-N-[2-methyl-1-phenyl-2-(1-pyrrolidinyl)butyl]-4,6-bis(trifluoromethyl)benzamide

Product 1

HCID 59347766N-[[1-(Dimethylamino)cyclopentyl](phenyl)methyl]-2-methyl-4,6-bis(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-4450c54fd72f4cd3b27f1a33f04b3787
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…