Dichloromethane → (5-Chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-methanol

HRID 2317617Notes

Reaction equation

HRID 2317617 reaction equation
[CH3:26][CH:27]([CH2:28][AlH:29][CH2:30][CH:31]([CH3:32])[CH3:33])[CH3:34].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([CH3:25])[c:6](-[c:19]3[cH:20][n:21][cH:22][cH:23][cH:24]3)[n:7]([CH2:11][O:12][C:13](=[O:14])[C:15]([CH3:16])([CH3:17])[CH3:18])[c:8]2[cH:9][cH:10]1.[Cl:35][CH2:36][Cl:37]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([CH3:25])[c:6](-[c:19]3[cH:20][n:21][cH:22][cH:23][cH:24]3)[n:7]([CH2:11][OH:12])[c:8]2[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 14487Diisobutylaluminum hydrideHCID 582155992,2-Dimethyl-propionic acid 5-chloro-3-methyl-2-pyridin-3-yl-indol-1-ylmethyl ester

Product 1

HCID 58215766(5-Chloro-3-methyl-2-pyridin-3-yl-indol-1-yl)-methanol

Sources & evidence

ORD record
ord-a16c540425a74ddebb04513a6d98260e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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