Potassium Cation → tert-butyl 7-(tert-butoxycarbonyl(methyl)amino)-5-(3-(ethylsulfonyl)phenyl)-8-methoxy-3-methyl-9H-pyrido[2,3-b]indole-9-carboxylate

HRID 2317701Notes

Reaction equation

HRID 2317701 reaction equation
[Br:1][c:2]1[c:3]2[c:4]3[c:5]([n:6]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[c:7]2[c:8]([O:20][CH3:21])[c:9]([N:11]([CH3:12])[C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[cH:10]1)[n:29][cH:30][c:31]([CH3:33])[cH:32]3.[CH2:34]([CH3:35])[S:36](=[O:37])(=[O:38])[c:39]1[cH:40][c:41]([B:45]([OH:46])[OH:47])[cH:42][cH:43][cH:44]1.[CH3:60][CH2:61][O:62][C:63]([CH3:64])=[O:65].[K+:54].[K+:55].[O-:56][C:57]([O-:58])=[O:59].[O:48]1[CH2:49][CH2:50][O:51][CH2:52][CH2:53]1.[cH:66]1[cH:67][cH:68][c:69]([P:70]([Pd:71]([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([P:91]([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[P:110]([c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)([c:117]2[cH:118][cH:119][cH:120][cH:121][cH:122]2)[c:123]2[cH:124][cH:125][cH:126][cH:127][cH:128]2)([c:129]2[cH:130][cH:131][cH:132][cH:133][cH:134]2)[c:135]2[cH:136][cH:137][cH:138][cH:139][cH:140]2)[cH:141][cH:142]1>>[c:2]1(-[c:41]2[cH:40][c:39]([S:36]([CH2:34][CH3:35])(=[O:37])=[O:38])[cH:44][cH:43][cH:42]2)[c:3]2[c:4]3[c:5]([n:6]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[c:7]2[c:8]([O:20][CH3:21])[c:9]([N:11]([CH3:12])[C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[cH:10]1)[n:29][cH:30][c:31]([CH3:33])[cH:32]3

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 164271023-Ethylsulfonylphenylboronic acidHCID 58880119tert-butyl 5-bromo-7-(tert-butoxycarbonyl(methyl)amino)-8-methoxy-3-methyl-9H-pyrido[2,3-b]indole-9-carboxylateHCID 178420554HCID 178420554, compound

Product 1

HCID 58880095tert-butyl 7-(tert-butoxycarbonyl(methyl)amino)-5-(3-(ethylsulfonyl)phenyl)-8-methoxy-3-methyl-9H-pyrido[2,3-b]indole-9-carboxylate

Sources & evidence

ORD record
ord-0a39531846ad4faf9d8ab7b53dbfcbf8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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