Hydrochloric Acid → Tetrahydro-pyran-4-carboxylic acid [7-aminomethyl-6-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-amide

HRID 2317836Notes

Reaction equation

HRID 2317836 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][c:9]1[cH:10][c:11]2[n:12]([cH:13][c:14]1-[c:15]1[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]1)[c:23]([NH:26][C:27](=[O:28])[CH:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1)[cH:24][n:25]2)([CH3:5])([CH3:6])[CH3:35].[ClH:36].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[NH2:7][CH2:8][c:9]1[cH:10][c:11]2[n:12]([cH:13][c:14]1-[c:15]1[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]1)[c:23]([NH:26][C:27](=[O:28])[CH:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1)[cH:24][n:25]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 57906481{6-(2,4-Dichloro-phenyl)-3-[(tetrahydro-pyran-4-carbonyl)-amino]-imidazo[1,2-a]pyridin-7-ylmethyl}-carbamic acid tert-butyl ester

Product 1

HCID 57906482Tetrahydro-pyran-4-carboxylic acid [7-aminomethyl-6-(2,4-dichloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-amide

Sources & evidence

ORD record
ord-4848cbf7da124cd4b4fc2574860c0615
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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