HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 10058334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 2-Chloro-4-methoxy-6-methylpyrimidine | HCID 12490571 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10058334 | HCID 10058334 | 51.1% |
Reaction Steps
In anhydrous tetrahydrofuran, 159 mg of 2-chloro-4-methoxy-6-methylpyrimidine was substituted with 68 mg of imidazole. The reaction mixture was treated according to the Procedure of Example 5 to yield 97 mg of 2-(1-imidazolyl)-4-methoxy-6-methylpyrimidine, recrystallized from n-hexane, having a melting point of 53°-54° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04849424 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-ab19f8767a0c4551ae71325587412845 |
| Source note | uspto-grants-1989_07 |