HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-1,2,4-Triazole → HCID 10679259, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | 2-Chloro-4-methoxy-6-methylpyrimidine | HCID 12490571 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10679259 | HCID 10679259 | 48.2% |
Reaction Steps
In anhydrous tetrahydrofuran, 159 mg of 2-chloro-4-methoxy-6-methylpyrimidine was substituted with 69 mg of 1,2,4-triazole. The reaction mixture was treated according to the procedure as in Example 5 to yield 92 mg of 4-methoxy-6-methyl-2-(1,2,4-triazol-1-yl)-pyrimidine, recrystallized from n-hexane, having a melting point of 142.5°-143° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04849424 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-ea28cb82fec64b66bd289f086b02e378 |
| Source note | uspto-grants-1989_07 |