反应详情

A solution of 5-chlorocarbonylphthalid (32 g, 0.16 mole) in THF (300 ml) is added to dimethylamine (40% v/v in water, 300 ml) and ice (100 g). The mixture is stirred for 1 hour. THF is evaporated off in vacuo and precipitated crystals are filtred off at 5° C. and washed with water (100 ml).

1. customTHF is evaporated off in vacuo
2. customprecipitated crystals
3. customare filtred off at 5° C.
4. washwashed with water (100 ml)