HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fumaric Acid → 116870-77-0
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | HCID 3088035 | HCID 3088035 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 116870-77-0 | HCID 6450690 | 84.5% |
Reaction Steps
To 100 ml of a tetrahydrofuran solution of 7.62 g of the resulting Compound 6 was added 100 ml of a tetrahydrofuran solution of 2.86 g of fumaric acid. The mixture was stirred under ice cooling. Separation of the precipitated crystals by filtration gave 8.85 g of 3-(2-aminophenyl)-2-(2-isopropylaminoethyl)isoindolin-1-one monofumarate (Compound 6').
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04849441 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-7e9f4462f48241388e6f3205464d4afe |
| Source note | uspto-grants-1989_07 |