Dichloromethane → 4-(2,3-Dichlorophenyl)piperidin-4-ol
Reaction equation
[CH2:30]([Cl:31])[Cl:32].[Cl:1][c:2]1[c:3]([C:9]2([OH:22])[CH2:10][CH2:11][N:12]([C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:13][CH2:14]2)[cH:4][cH:5][cH:6][c:7]1[Cl:8].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[Cl:1][c:2]1[c:3]([C:9]2([OH:22])[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[cH:4][cH:5][cH:6][c:7]1[Cl:8]Participants
4
Sources & evidence
- ORD record
- ord-e628387dc0334037b6d8cb6b2d261908
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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