Potassium Cation → Dimethyl 2',5'-difluoro-1,1'-biphenyl-2,4-dicarboxylate

HRID 2318846Notes

Reaction equation

HRID 2318846 reaction equation
[C:34](=[O:35])([O-:36])[O-:37].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[c:8]([C:17](=[O:18])[O:19][CH3:20])[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16]1)(=[O:21])=[O:22].[F:23][c:24]1[c:25]([B:31]([OH:32])[OH:33])[cH:26][c:27]([F:30])[cH:28][cH:29]1.[K+:38].[K+:39].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[cH:45]1[cH:46][cH:47][c:48]([P:49]([Pd:50]([P:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)([P:70]([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[P:89]([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)([c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)[cH:120][cH:121]1>>[c:7]1(-[c:25]2[c:24]([F:23])[cH:29][cH:28][c:27]([F:30])[cH:26]2)[c:8]([C:17](=[O:18])[O:19][CH3:20])[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 2734335(2,5-Difluorophenyl)boronic acidHCID 120175464-[[(Trifluoromethyl)sulfonyl]oxy]-1,3-benzenedicarboxylic acid dimethyl esterHCID 178420554HCID 178420554, compound

Product 1

HCID 57707138Dimethyl 2',5'-difluoro-1,1'-biphenyl-2,4-dicarboxylate

Sources & evidence

ORD record
ord-e35bf8585f5947548680996b303effcc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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