Dichloromethane → 2-cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid [1-(1-hydroxy-1-methyl-ethyl)-cyclopentyl]-amide
Reaction equation
[Cl:40][CH2:41][Cl:42].[OH:1][C:2]([CH3:3])([CH3:4])[C:5]1([NH:10][C:11](=[O:12])[c:13]2[cH:14][n:15]([CH2:25][O:26][CH2:27][CH2:28][Si:29]([CH3:30])([CH3:31])[CH3:32])[c:16]3[n:17][cH:18][c:19]([CH:22]4[CH2:23][CH2:24]4)[n:20][c:21]23)[CH2:6][CH2:7][CH2:8][CH2:9]1.[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[OH:1][C:2]([CH3:3])([CH3:4])[C:5]1([NH:10][C:11](=[O:12])[c:13]2[cH:14][nH:15][c:16]3[n:17][cH:18][c:19]([CH:22]4[CH2:23][CH2:24]4)[n:20][c:21]23)[CH2:6][CH2:7][CH2:8][CH2:9]1Participants
4
Sources & evidence
- ORD record
- ord-e4f778a5d328415eb115aba5f1a8cbfe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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