Hydrochloric Acid → Diflunisal

HRID 2319134Notes

Reaction equation

HRID 2319134 reaction equation
[ClH:22].[F:1][c:2]1[c:3](-[c:9]2[cH:10][cH:11][c:12]([OH:19])[c:13]([C:14](=[O:15])[O:16][CH3:17])[cH:18]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[Na+:21].[OH-:20]>>[F:1][c:2]1[c:3](-[c:9]2[cH:10][cH:11][c:12]([OH:19])[c:13]([C:14](=[O:15])[OH:16])[cH:18]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 491921Methyl 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylate

Product 1

HCID 3059Diflunisal

Sources & evidence

ORD record
ord-9dc1c63a1ff0480da5fbe01d262ac815
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…