Sodium ion → 7-Benzyloxy-4-(4-bromo-2,6-difluoroanilino)-6-methoxyquinazoline
Reaction equation
[Br:3][c:4]1[cH:5][c:6]([F:12])[c:7]([NH2:8])[c:9]([F:11])[cH:10]1.[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][c:21]1[c:22]([O:32][CH3:33])[cH:23][c:24]2[c:25]([Cl:31])[n:26][cH:27][n:28][c:29]2[cH:30]1.[H-:1].[Na+:2].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[Br:3][c:4]1[cH:5][c:6]([F:12])[c:7]([NH:8][c:25]2[c:24]3[cH:23][c:22]([O:32][CH3:33])[c:21]([O:20][CH2:13][c:14]4[cH:15][cH:16][cH:17][cH:18][cH:19]4)[cH:30][c:29]3[n:28][cH:27][n:26]2)[c:9]([F:11])[cH:10]1Participants
6
Sources & evidence
- ORD record
- ord-b0ceedb5c8b64fc68c6f4df4590eaf00
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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