HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → S-(2,4,5-Trichlorophenyl) 4-(hydroxy)thiobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-{[(2,4,5-Trichlorophenyl)sulfanyl]carbonyl}phenyl acetate | HCID 71333216 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | S-(2,4,5-Trichlorophenyl) 4-(hydroxy)thiobenzoate | HCID 86743245 | 60.8% |
Reaction Steps
S-(2,4,5-Trichlorophenyl) 4-(acetoxy)thiobenzoate (10 g) in tetrahydrofuran was treated with 25 ml of 5.6M hydrochloric acid and stirred at room temperature overnight. The solvents were evaporated in vacuo to give a product which was purified by column chromatography (silica; ethyl acetate-hexane mixtures as eluant) to afford the title compound (5.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04849419 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-c9e72c98bdc84eb39bae8f59c7a67c7d |
| Source note | uspto-grants-1989_07 |