反应详情

To a suspension of 30 g of methyl 2-(aminosulfonyl)benzeneacetate in 125 ml of absolute ethanol was added 7.8 g of hydrazine monohydrate. The suspension was heated at reflux for about 16 hours, then cooled in an ice-water bath. A viscous oil formed which solidified on continued stirring and cooling. The suspension was filtered and suction-dried to give 23 g of the subject compound; m.p. 116°-125° C. Anal. Calc. for: C8H11N3O3S; C,41.9; H,4.8; N,18.3. Found: C,41.5; H,4.9; N,18.0.

1. temperatureThe suspension was heated
2. temperatureat reflux for about 16 hours
3. temperaturecooled in an ice-water bath
4. customA viscous oil formed which
5. temperaturecooling
6. filtrationThe suspension was filtered
7. customsuction-dried