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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2319790Generated: October 31, 2026

Hydrochloric Acid → 4-(4-Chloro-2-fluoroanilino)-7-((2-cyano4-pyridyl)methoxy)-6-methoxyquinazoline

https://huagongshe.com/reaction/2319790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactant4-(Chloromethyl)pyridine-2-carbonitrileHCID 20390611—
Reactant4-(4-Chloro-2-fluorophenylamino)-7-hydroxy-6-methoxyquinazolineHCID 135513720—
Product4-(4-Chloro-2-fluoroanilino)-7-((2-cyano4-pyridyl)methoxy)-6-methoxyquinazolineHCID 22625077—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-116fcbc4c82c4cdb80f11efceef801f2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)