HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → Potassium 2-cyanonicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 2-cyanopyridine-3-carboxylate | HCID 12747366 | — |
| Solvent | Water | HCID 962 | — |
| Product | Potassium 2-cyanonicotinate | HCID 23690323 | 603.4% |
Reaction Steps
Ethyl 2-cyanonicotinate (compound 2) (20 g; 0.113 mol) is added to a solution of potassium hydroxide (6 g; 0.017 mol) in distilled water (150 cc). The mixture is then allowed to stand for 10 hours at 25° C., and then washed with ether (2×50 cc). The aqueous solution is then evaporated to dryness to give compound 3 (19.1 g; m.p. 300° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04851396 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-5267c27530ad4344822b689e0a1b31c2 |
| Source note | uspto-grants-1989_07 |