Carbonate Ion → 3-(4-Hydroxymethylphenyl)propynoic acid (4-prop-1-ynylphenyl)amide

HRID 2320179Notes

Reaction equation

HRID 2320179 reaction equation
[C:16](#[C:17][CH3:18])[c:19]1[cH:20][cH:21][c:22]([NH:25][C:26]([C:27]#[CH:28])=[O:29])[cH:23][cH:24]1.[C:1](=[O:2])([O-:3])[O-:4].[Cs+:5].[Cs+:6].[Cu:30][I:31].[I:7][c:8]1[cH:9][cH:10][c:11]([CH2:12][OH:13])[cH:14][cH:15]1>>[c:8]1([C:28]#[C:27][C:26]([NH:25][c:22]2[cH:21][cH:20][c:19]([C:16]#[C:17][CH3:18])[cH:24][cH:23]2)=[O:29])[cH:9][cH:10][c:11]([CH2:12][OH:13])[cH:14][cH:15]1

Participants

6

Reactant 5

HCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 290124-Iodobenzyl alcoholHCID 104967Cesium cation2×HCID 86060737Propynoic acid-(4-prop-1-ynylphenyl)amide

Product 1

HCID 688177323-(4-Hydroxymethylphenyl)propynoic acid (4-prop-1-ynylphenyl)amide

Sources & evidence

ORD record
ord-79deb2e7973040c18a1e340c26c85e38
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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