Dichloromethane → 8-Fluoro-4-[3-(6-methyl-pyridin-3-yl)-phenyl]-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:15][C:16]([CH2:17][C:18](=[O:5])[c:20]2[cH:21][c:22](-[c:26]3[cH:27][n:28][c:29]([CH3:32])[cH:30][cH:31]3)[cH:23][cH:24][cH:25]2)=[O:33])[cH:10][c:11]([F:14])[cH:12][cH:13]1)([CH3:6])([CH3:19])[CH3:34].[Cl:42][CH2:43][Cl:44].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[N:7]1=[C:18]([c:20]2[cH:21][c:22](-[c:26]3[cH:27][n:28][c:29]([CH3:32])[cH:30][cH:31]3)[cH:23][cH:24][cH:25]2)[CH2:17][C:16](=[O:33])[NH:15][c:9]2[c:8]1[cH:13][cH:12][c:11]([F:14])[cH:10]2Participants
4
Sources & evidence
- ORD record
- ord-1f8274708b3046efbb9262ec503e65a9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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