1-Butanol → HCID 178452774, compound

HRID 2320202Notes

Reaction equation

HRID 2320202 reaction equation
[Br:1][c:2]1[c:3]([F:19])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12](=[O:13])[CH:14]1[C:15]([F:17])([F:18])[CH2:16]1.[CH2:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH:39]([CH3:40])[CH3:41])[CH3:42].[CH2:43]([OH:44])[CH2:45][CH2:46][CH3:47].[NH:20]1[CH2:21][CH:22]([NH:26][C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:23][CH2:24][CH2:25]1>>[Br:1][c:2]1[c:3]([N:20]2[CH2:21][CH:22]([NH:26][C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:23][CH2:24][CH2:25]2)[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12](=[O:13])[CH:14]1[C:15]([F:17])([F:18])[CH2:16]1

Participants

5

Reactant 4

HCID 2631-ButanolHCID 81531DiisopropylethylamineHCID 42330413-(Boc-amino)piperidineHCID 60205543N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,2-difluorocyclopropanecarboxamide

Product 1

HCID 178452774HCID 178452774, compound

Sources & evidence

ORD record
ord-90f9942e45d9408391c4361f9bf517f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…