Acetic Acid → 3-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-{[5-(hydroxymethyl)pyrazin-2-yl]methyl}-6-methylpyridin-2(1H)-one
Reaction equation
[BH4-:37].[Br:1][c:2]1[c:3](=[O:31])[n:4]([CH2:19][c:20]2[n:21][cH:22][c:23]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[n:24][cH:25]2)[c:5]([CH3:18])[cH:6][c:7]1[O:8][CH2:9][c:10]1[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]1.[C:41]([OH:42])([CH3:43])([CH3:44])[CH3:45].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:39][OH:40].[CH3:46][C:47](=[O:48])[OH:49].[Na+:38]>>[Br:1][c:2]1[c:3](=[O:31])[n:4]([CH2:19][c:20]2[n:21][cH:22][c:23]([CH2:26][OH:27])[n:24][cH:25]2)[c:5]([CH3:18])[cH:6][c:7]1[O:8][CH2:9][c:10]1[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-590314244a9e409891278712888d0b8a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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