Dimethylamine → 4-(4-Chloro-2-fluoro-phenylamino)-7-(3-dimethylaminopropoxy)-6-methoxy-quinoline-3-carbonitrile
Reaction equation
[CH3:31][NH:32][CH3:33].[Cl:1][c:2]1[cH:3][c:4]([F:28])[c:5]([NH:8][c:9]2[c:10]([C:26]#[N:27])[cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH2:22][CH2:23][CH2:24][Cl:25])[c:16]([O:19][CH3:20])[cH:17][c:18]23)[cH:6][cH:7]1.[I-:30].[Na+:29].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[Cl:1][c:2]1[cH:3][c:4]([F:28])[c:5]([NH:8][c:9]2[c:10]([C:26]#[N:27])[cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH2:22][CH2:23][CH2:24][N:32]([CH3:31])[CH3:33])[c:16]([O:19][CH3:20])[cH:17][c:18]23)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6dcf015b201d4fb39a9e3b5c7c919d5a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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