Dichloromethane → 4-(3,3-Difluoroazetidin-1-yl)piperidine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[CH2:15][C:16]([F:18])([F:19])[CH2:17]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:20][CH2:21][Cl:22].[F:23][C:24]([F:25])([F:26])[C:27]([OH:28])=[O:29]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[CH2:15][C:16]([F:18])([F:19])[CH2:17]2)[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-570ab617b8d34aeea2f924d29d4322f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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