Trifluoroacetic acid → HCID 178489596, compound

HRID 2321188Notes

Reaction equation

[F:1][c:2]1[cH:3][c:4]([NH:31][C:32]([CH2:33][C:34](=[O:35])[NH:36][c:37]2[c:38]([O:43][CH3:44])[cH:39][cH:40][cH:41][cH:42]2)=[O:45])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19][cH:20][n:21]([CH2:23][O:24][CH2:25][CH2:26][Si:27]([CH3:28])([CH3:29])[CH3:30])[cH:22]1)[s:17]2.[F:46][C:47]([F:48])([F:49])[C:50]([OH:51])=[O:52]>>[F:1][c:2]1[cH:3][c:4]([NH:31][C:32]([CH2:33][C:34](=[O:35])[NH:36][c:37]2[c:38]([O:43][CH3:44])[cH:39][cH:40][cH:41][cH:42]2)=[O:45])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19][cH:20][nH:21][cH:22]1)[s:17]2

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 58790420N1-(3-Fluoro-4-(2-(1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-methoxyphenyl)malonamide

Product 1

HCID 178489596HCID 178489596, compound

Sources & evidence

ORD record: ord-b1e0ed7224a04414a75fc1b33ea56c27
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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