Tetrahydrofuran → N-(7-bromo-3-chloro-1-fluoro-5-(2-hydroxyethyl)-5H-chromeno[2,3-c]pyridin-5-yl)-2-methylpropane-2-sulfinamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:15]([cH:16][cH:17]1)[O:14][c:7]1[c:6]([cH:11][c:10]([Cl:12])[n:9][c:8]1[F:13])[C:5]2([NH:18][S:19](=[O:20])[C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:25][C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32].[CH2:34]([Al+:35][CH2:36][CH:37]([CH3:38])[CH3:39])[CH:40]([CH3:41])[CH3:42].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[H-:33]>>[Br:1][c:2]1[cH:3][c:4]2[c:15]([cH:16][cH:17]1)[O:14][c:7]1[c:6]([cH:11][c:10]([Cl:12])[n:9][c:8]1[F:13])[C:5]2([NH:18][S:19](=[O:20])[C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:25][CH2:26][OH:27]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e81cd27c268343388737d8c2d17aa820
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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