Hydrochloric Acid → 1-(4-Nitrophenyl)piperidine-4-carboxylic acid

HRID 2321391Notes

Reaction equation

HRID 2321391 reaction equation
[C:55](=[O:56])([O-:57])[O-:58].[CH2:28]([N+:29]([CH2:30][CH2:31][CH2:32][CH3:33])([CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH3:44].[CH2:2]([N+:3]([CH2:4][CH2:5][CH2:6][CH3:7])([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:12][CH2:13][CH2:14][CH3:15])[CH2:16][CH2:17][CH3:18].[CH3:62][OH:63].[CH3:64][S:65]([CH3:66])=[O:67].[ClH:61].[F:45][c:46]1[cH:47][cH:48][c:49]([N+:52](=[O:53])[O-:54])[cH:50][cH:51]1.[K+:59].[K+:60].[NH:19]1[CH2:20][CH2:21][CH:22]([C:23](=[O:24])[O-:25])[CH2:26][CH2:27]1.[OH-:1].[OH2:68]>>[N:19]1([c:46]2[cH:47][cH:48][c:49]([N+:52](=[O:53])[O-:54])[cH:50][cH:51]2)[CH2:20][CH2:21][CH:22]([C:23](=[O:24])[OH:25])[CH2:26][CH2:27]1

Participants

11

Reactant 10

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 887MethanolHCID 961HydroxideHCID 962WaterHCID 9590p-FluoronitrobenzeneHCID 16028Tetrabutylammonium2×HCID 19660Carbonate IonHCID 22468532HCID 22468532, compound

Product 1

HCID 27672651-(4-Nitrophenyl)piperidine-4-carboxylic acid

Sources & evidence

ORD record
ord-f850793d24a440b5a806faac4ca0d7b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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