Chloroform → (1H-benzo[d]imidazol-2-yl)(4-(3-(piperidin-4-yl)pyrazin-2-yloxy)phenyl)methanone

HRID 2321438Notes

Reaction equation

HRID 2321438 reaction equation
[CH:45]([Cl:46])([Cl:47])[Cl:48].[F:38][C:39]([F:40])([F:41])[C:42]([OH:43])=[O:44].[nH:1]1[c:2]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([O:16][c:17]3[c:18]([CH:23]4[CH2:24][CH2:25][N:26]([C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:27][CH2:28]4)[n:19][cH:20][cH:21][n:22]3)[cH:36][cH:37]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[nH:1]1[c:2]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([O:16][c:17]3[c:18]([CH:23]4[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]4)[n:19][cH:20][cH:21][n:22]3)[cH:36][cH:37]2)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

4

Reactant 3

HCID 6212ChloroformHCID 6422Trifluoroacetic acidHCID 59351389tert-butyl 4-(3-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidine-1-carboxylate

Product 1

HCID 59351142(1H-benzo[d]imidazol-2-yl)(4-(3-(piperidin-4-yl)pyrazin-2-yloxy)phenyl)methanone

Sources & evidence

ORD record
ord-5b24da8ee5fd470c9785e92c8ff39b5f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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